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fear conditioning chamber  (Coulbourn Instruments)

 
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    Structured Review

    Coulbourn Instruments fear conditioning chamber
    Fear Conditioning Chamber, supplied by Coulbourn Instruments, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fear+conditioning+chamber/chamber+conditioning/pmc13196587-36-7-10
    Average 86 stars, based on 1 article reviews
    fear conditioning chamber - by Bioz Stars, 2026-09
    86/100 stars

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    Related Articles

    other:

    Article Title: The lateralized LC-NAergic system distinguishes vicarious versus direct fear in mice
    Article Snippet: For contextual fear conditioning, mice were placed in a fear conditioning chamber (Coulbourn Instruments) and allowed to explore for 5 min.

    Mouse Assay:

    Article Title: Astroglial TNFR2 signaling regulates hippocampal synaptic function and plasticity in a sex dependent manner.
    Article Snippet: Astrocytes participate in synaptic transmission and plasticity through tightly regulated, bidirectional communication with preand post-synaptic neurons, as well as microglia and oligodendrocytes.. A key component of astrocyte-mediated synaptic regulation is the cytokine tumor necrosis factor (TNF).. TNF signals via two cognate receptors, TNFR1 and TNFR2, both expressed in astrocytes.

    Article Title: Dynamic representations of valence in anterior cingulate cortex in mice
    Article Snippet: .. Mice habituated to the tethering procedure and fear conditioning chamber (Coulbourn Instruments, Allentown, PA) with two layers of sound attenuation (chamber, Harvard Apparatus, Holliston, MA; cabinet, ROOM, New York, NY) for 5–15 minutes per day for 5 days. ..

    Isolation:

    Article Title: Astroglial TNFR2 signaling regulates hippocampal synaptic function and plasticity in a sex dependent manner.
    Article Snippet: Astrocytes participate in synaptic transmission and plasticity through tightly regulated, bidirectional communication with preand post-synaptic neurons, as well as microglia and oligodendrocytes.. A key component of astrocyte-mediated synaptic regulation is the cytokine tumor necrosis factor (TNF).. TNF signals via two cognate receptors, TNFR1 and TNFR2, both expressed in astrocytes.



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    Image Search Results


    Fear conditioning increases pip-induced local field potential (LFP) in control but not in Htr3a-KO during retrieval. A) Schema of the experimental setup for intracerebral recordings in head-fixed mice in the prelimbic cortex (PrL), infralimbic cortex (IL) and basolateral amygdala (BLA). B) Representative examples (1 mouse per condition) of pip-evoked potentials (1-100 Hz), z-normalized to 500ms pre-pip period, in WT and Htr3a-KO mice. Mean of all CS trains (420 pips, solid lines) ± SEM. C) Average pip-evoked LFP ± SEM across the 30 pips of each CS train in WT mice (n = 8; LFP data of 4/12 WT mice were excluded due to poor signal quality) in the PrL, IL, and BLA during habituation and retrieval days. Data are shown across the 14 CS trains (labelled t1 to t14) and were z-normalized to the 500 ms pre-pip baseline. In the PrL, there was a main effect of Days (p = 0.049) and of CS train (p = 0.002). In the IL, there was a main effect of days (p = 0.04), whereas the effect of CS train was not significant (p = 0.77). In the BLA, there was a main effect of days (p = 0.009) and of CS train (p < 0.001). Two-way ANOVA followed by Bonferroni post-hoc tests (*p < 0.05, **p < 0.01, ***p < 0.001). D) Pip-evoked responses in the Htr3a-KO mice (n = 8), no main effects were detected. E) Averaged LFP response of the first 3 CS during habituation and retrieval days, z-normalized to the 500ms pre-pip-onset in WT (main effect of Days: p =0.004, Bonferroni multiple comparison for PrL, IL and BLA: all p < 0.001) and Htr3a-KO (main effect of Days: p = 0.201). F) LFP responses of the first 3 CS in all mice during habituation (main effect of genotype: p = 0.275) and during retrieval (main effect of genotype: p = 0.038, Bonferroni multiple comparison for PrL: p = 0.489, IL: p = 0.097, BLA: *p = 0.043).

    Journal: bioRxiv

    Article Title: Htr3a receptors control attenuation of fear responses by modulating the corticolimbic activity and synchronization

    doi: 10.64898/2026.03.16.711072

    Figure Lengend Snippet: Fear conditioning increases pip-induced local field potential (LFP) in control but not in Htr3a-KO during retrieval. A) Schema of the experimental setup for intracerebral recordings in head-fixed mice in the prelimbic cortex (PrL), infralimbic cortex (IL) and basolateral amygdala (BLA). B) Representative examples (1 mouse per condition) of pip-evoked potentials (1-100 Hz), z-normalized to 500ms pre-pip period, in WT and Htr3a-KO mice. Mean of all CS trains (420 pips, solid lines) ± SEM. C) Average pip-evoked LFP ± SEM across the 30 pips of each CS train in WT mice (n = 8; LFP data of 4/12 WT mice were excluded due to poor signal quality) in the PrL, IL, and BLA during habituation and retrieval days. Data are shown across the 14 CS trains (labelled t1 to t14) and were z-normalized to the 500 ms pre-pip baseline. In the PrL, there was a main effect of Days (p = 0.049) and of CS train (p = 0.002). In the IL, there was a main effect of days (p = 0.04), whereas the effect of CS train was not significant (p = 0.77). In the BLA, there was a main effect of days (p = 0.009) and of CS train (p < 0.001). Two-way ANOVA followed by Bonferroni post-hoc tests (*p < 0.05, **p < 0.01, ***p < 0.001). D) Pip-evoked responses in the Htr3a-KO mice (n = 8), no main effects were detected. E) Averaged LFP response of the first 3 CS during habituation and retrieval days, z-normalized to the 500ms pre-pip-onset in WT (main effect of Days: p =0.004, Bonferroni multiple comparison for PrL, IL and BLA: all p < 0.001) and Htr3a-KO (main effect of Days: p = 0.201). F) LFP responses of the first 3 CS in all mice during habituation (main effect of genotype: p = 0.275) and during retrieval (main effect of genotype: p = 0.038, Bonferroni multiple comparison for PrL: p = 0.489, IL: p = 0.097, BLA: *p = 0.043).

    Article Snippet: On D5, mice underwent fear conditioning in a sound-attenuating conditioning chamber (17 × 17 × 25 cm; Ugo Basile, 46003), equipped with a grid floor of stainless-steel bars for shock delivery.

    Techniques: Control, Comparison